Expression and biological activity of two recombinant polypeptides related to subunit 1 of the interferon-a receptor

Abnormal production of interferon alpha (IFN-a) has been found in certain autoimmune diseases and can be also observed after prolonged therapy with IFN-a. IFN-a can contribute to the pathogenesis of allograft rejection in bone marrow transplants. Therefore, the development of IFN-a inhibitors as a s...

Full description

Bibliographic Details
Main Authors: S. Yoon, R.D.C. Hirata, N.Y. Nguyen, R. Curi, M. Russo, M.H. Hirata
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2000-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700007