Targeting oncogenic functions of miR-301a in head and neck squamous cell carcinoma by PI3K/PTEN and MEK/ERK pathways

Treatment of head and neck squamous cell carcinomas (HNSCC), the sixth most frequent cancer worldwide, remains challenging. miRNA dysregulation is closely linked to tumorigenesis and tumor progression, thus emerging as suitable targets for cancer treatment. Transcriptomic analysis of TCGA HNSCC data...

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Main Authors: Rocío Granda-Díaz, Lorea Manterola, Francisco Hermida-Prado, René Rodríguez, Laura Santos, Vanessa García-de-la-Fuente, María Teresa Fernández, M. Daniela Corte-Torres, Juan P. Rodrigo, Saúl Álvarez-Teijeiro, Charles H. Lawrie, Juana M. Garcia-Pedrero
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223003001