Targeting oncogenic functions of miR-301a in head and neck squamous cell carcinoma by PI3K/PTEN and MEK/ERK pathways

Targeting oncogenic functions of miR-301a in head and neck squamous cell carcinoma by PI3K/PTEN and MEK/ERK pathways

Treatment of head and neck squamous cell carcinomas (HNSCC), the sixth most frequent cancer worldwide, remains challenging. miRNA dysregulation is closely linked to tumorigenesis and tumor progression, thus emerging as suitable targets for cancer treatment. Transcriptomic analysis of TCGA HNSCC data...

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Bibliographic Details
Main Authors: Rocío Granda-Díaz, Lorea Manterola, Francisco Hermida-Prado, René Rodríguez, Laura Santos, Vanessa García-de-la-Fuente, María Teresa Fernández, M. Daniela Corte-Torres, Juan P. Rodrigo, Saúl Álvarez-Teijeiro, Charles H. Lawrie, Juana M. Garcia-Pedrero
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Head and neck squamous cell carcinoma
miR-301a
Therapeutic target
Signaling
PI3K
ERK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223003001

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