The tetraspanin TSPAN5 regulates AMPAR exocytosis by interacting with the AP4 complex

Intracellular trafficking of AMPA receptors is a tightly regulated process which involves several adaptor proteins, and is crucial for the activity of excitatory synapses both in basal conditions and during synaptic plasticity. We found that, in rat hippocampal neurons, an intracellular pool of the...

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Bibliographic Details
Main Authors: Edoardo Moretto, Federico Miozzo, Anna Longatti, Caroline Bonnet, Francoise Coussen, Fanny Jaudon, Lorenzo A Cingolani, Maria Passafaro
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/76425