General ADP-Ribosylation Mechanism Based on the Structure of ADP-Ribosyltransferase–Substrate Complexes

ADP-ribosylation is a ubiquitous modification of proteins and other targets, such as nucleic acids, that regulates various cellular functions in all kingdoms of life. Furthermore, these ADP-ribosyltransferases (ARTs) modify a variety of substrates and atoms. It has been almost 60 years since ADP-rib...

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Bibliographic Details
Main Authors: Hideaki Tsuge, Noriyuki Habuka, Toru Yoshida
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/16/7/313