Identification of rare variants of allergic rhinitis based on whole genome sequencing and gene expression profiling: A preliminary investigation in four families

Background: Despite the success of genome-wide association studies for allergic rhinitis (AR), no definitive causal variants have been identified, and a substantial portion of the heritability of the disease is yet to be discovered. Methods: Four families, each with at least 1 parent and one child s...

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Bibliographic Details
Main Authors: Yuan Zhang, Jingyun Li, Yali Zhao, Chengshuo Wang, Luo Zhang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119306672