Endothelial Agrin Is Dispensable for Normal and Tumor Angiogenesis

Recently, the extracellular matrix protein agrin has been reported to promote tumor angiogenesis that supports tumorigenesis and metastasis; however, there is a lack of in vivo genetic evidence to prove whether agrin derived from the tumors or endothelial cells (ECs) systemically should be the thera...

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Bibliographic Details
Main Authors: Peng Ye, Zelong Fu, Jeff Yat-Fai Chung, Xiaoyun Cao, Ho Ko, Xiao Yu Tian, Patrick Ming-Kuen Tang, Kathy O. Lui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.810477/full