The development of an in-situ biopolymer-based floating gel for the oral delivery of metformin hydrochloride

Diabetes remains a global public health threat because of its increasing prevalence and mortality, especially in people under the age of 25. Metformin hydrochloride (HCl), as recommended by American Diabetes Association in 2022, is the first-line therapy for type 2 diabetes in adults. Metformin has...

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Bibliographic Details
Main Authors: Ruedeekorn Wiwattanapatapee, Kalayamas Klabklay, Nontawat Raksajit, Worrawee Siripruekpong, Nattawut Leelakanok, Arpa Petchsomrit
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023020030