Thrombomodulin activation driven by LXR agonist attenuates renal injury in diabetic nephropathy

ObjectiveInflammation and thrombosis are recognized as interrelated biological processes. Both thrombomodulin (TM) and factor XIII-A (FXIII-A) are involved in inflammation and coagulation process. However, their role in the pathogenesis of diabetic nephropathy (DN) remains unclear. In vitro study, t...

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Bibliographic Details
Main Authors: Wei Wang, Song Wu, Amanda Y. Wang, Tao Wu, Haojun Luo, Jia Wei Zhao, Jin Chen, Yi Li, Hanlu Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.916620/full