Proinsulin C-peptide inhibits high glucose-induced migration and invasion of ovarian cancer cells

Proinsulin C-peptide inhibits high glucose-induced migration and invasion of ovarian cancer cells

Proinsulin C-peptide, a biologically active polypeptide released from pancreatic β-cells, is known to prevent hyperglycemia-induced microvascular leakage; however, the role of C-peptide in migration and invasion of cancer cells is unknown. Here, we investigated high glucose-induced migration and inv...

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Bibliographic Details
Main Authors: Eun-Bin Kim, Hye-Yoon Jeon, Yung-Taek Ouh, Ah-Jun Lee, Chan-Hee Moon, Sung Hun Na, Kwon-Soo Ha
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
C-peptide
High glucose
Invasion
Migration
Ovarian cancer
Transglutaminase 2
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001136

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http://www.sciencedirect.com/science/article/pii/S0753332224001136

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