Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway

Protective effect of Tetrandrine on optic nerve by inhibiting glial activation through NF-κB pathway

Introduction: This study aimed to explore the effect and molecular mechanism of Tetrandrine (Tet) onlipopolysaccharide (LPS)-induceduveitis andoptic nerve injury in vivo and in vitro. Methods: Uveitis was induced by LPS injected into the hindlimb foot pad of Wistar rats and was intervened by retroey...

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Bibliographic Details
Main Authors: Weiyi Li, Jing Cao, Jian Liu, Shuiling Chen, Min Dai, Mingming Zhang, Xinyue Hou, Jianquan Wang, Zefeng Kang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Glaucoma
Glial cells
Neuroinflammation
Nuclear factor kappa B
Tetrandrine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024007801

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http://www.sciencedirect.com/science/article/pii/S2405844024007801

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