High Expression of Cancer-IgG Is Associated With Poor Prognosis and Radioresistance via PI3K/AKT/DNA-PKcs Pathway Regulation in Lung Adenocarcinoma

High Expression of Cancer-IgG Is Associated With Poor Prognosis and Radioresistance via PI3K/AKT/DNA-PKcs Pathway Regulation in Lung Adenocarcinoma

BackgroundLung adenocarcinoma (LUAD) is the dominant type of lung neoplasms, and radiotherapy is its mainstay treatment, yet poor prognosis caused by radioresistance remains problematic. Cancer-derived immunoglobulin G (cancer-IgG) has been detected in multiple cancers and plays important roles in c...

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Bibliographic Details
Main Authors: Xiongtao Yang, Guohui Wang, Jing You, Runchuan Gu, Xiaohong Xu, Changdan Xu, Hao Wang, Ruisong Zhao, Xiaoyan Qiu, Guangying Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
cancer-IgG
lung adenocarcinoma
radioresistance
PI3K/AKT/DNA-PKcs pathway
RP215
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.675397/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.675397/full

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