The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics

Abstract Polyploid cells contain more than two copies of each chromosome. Polyploidy has important roles in development, evolution, and tissue regeneration/repair, and can arise as a programmed polyploidization event or be triggered by stress. Cancer cells are often polyploid. C. elegans nematodes a...

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Bibliographic Details
Main Authors: Kelly R. Misare, Elizabeth A. Ampolini, Hyland C. Gonzalez, Kaitlan A. Sullivan, Xin Li, Camille Miller, Bintou Sosseh, Jaclyn B. Dunne, Christina Voelkel-Johnson, Kacy L. Gordon, Jessica H. Hartman
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45225-w