The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics
Abstract Polyploid cells contain more than two copies of each chromosome. Polyploidy has important roles in development, evolution, and tissue regeneration/repair, and can arise as a programmed polyploidization event or be triggered by stress. Cancer cells are often polyploid. C. elegans nematodes a...
Main Authors: | Kelly R. Misare, Elizabeth A. Ampolini, Hyland C. Gonzalez, Kaitlan A. Sullivan, Xin Li, Camille Miller, Bintou Sosseh, Jaclyn B. Dunne, Christina Voelkel-Johnson, Kacy L. Gordon, Jessica H. Hartman |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-45225-w |
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