Promoter hypomethylation and overexpression of TSTD1 mediate poor treatment response in breast cancer

Promoter hypomethylation and overexpression of TSTD1 mediate poor treatment response in breast cancer

Epigenetic alterations play a pivotal role in cancer treatment outcomes. Using the methylation array data and The Cancer Genome Atlas (TCGA) dataset, we observed the hypomethylation and upregulation of thiosulfate sulfurtransferase–like domain containing 1 (TSTD1) in patients with breast cancer. We...

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Bibliographic Details
Main Authors: Muhamad Ansar, Le Thi Anh Thu, Chin-Sheng Hung, Chih-Ming Su, Man-Hsu Huang, Li-Min Liao, Yu-Mei Chung, Ruo-Kai Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
TSTD1
breast cancer
DNA methylation
hypomethylation
chemotherapy
hormone therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1004261/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1004261/full

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