Competition of IL-1 and IL-1ra determines lymphocyte response to delayed stimulation with PHA

Background: Human peripheral blood mononuclear cells (PBMC) left in microcultures for 24 h without mitogen do not respond to subsequent stimulation with PHA. They regain reactivity if the native culture medium is absorbed with other party lymphocytes or partially replaced with the medium from a PHA-...

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Bibliographic Details
Main Authors: Marek P. Dąbrowski, Wanda Stankiewicz, Tadeusz Płusa, Andrzej Chciałowski, Stanisław Szmigielski
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350124376