Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways

Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways

In schizophrenia, a single latent trait underlies psychosis, hostility, excitation, mannerism, negative (PHEMN) symptoms, formal thought disorders (FTD) and psychomotor retardation (PMR). Schizophrenia is accompanied by a breakdown of gut and blood-brain-barrier (BBB) pathways, increased tryptophan...

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Bibliographic Details
Main Authors: Maes Michael, Vojdani Aristo, Geffard Michel, Moreira Estefania G., Barbosa Decio S., Michelin Ana Paula, Semeão Laura de Oliveira, Sirivichayakul Sunee, Kanchanatawan Buranee
Format: Article
Language:English
Published: De Gruyter 2019-11-01
Series:Biomolecular Concepts
Subjects:
schizophrenia
inflammation
oxidative stress
neuro-immune
gut bacteria
antioxidants
Online Access:https://doi.org/10.1515/bmc-2019-0023

Internet

https://doi.org/10.1515/bmc-2019-0023

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