HSF1 overexpression enhances oncolytic effect of replicative adenovirus

<p>Abstract</p> <p>Background</p> <p>E1B55kD deleted oncolytic adenovirus was designed to achieve cancer-specific cytotoxicity, but showed limitations in clinical study. To find a method to increase its efficacy, we investigated the correlation between oncolytic effect...

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Bibliographic Details
Main Authors: Deng Youwen, Fan Rong, Dai Zhehao, Wang Cheng, Lv Guohua, Lu Guangxiu
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/44