Molecular glue-mediated targeted protein degradation: A novel strategy in small-molecule drug development
Summary: Small-molecule drugs are effective and thus most widely used. However, their applications are limited by their reliance on active high-affinity binding sites, restricting their target options. A breakthrough approach involves molecular glues, a novel class of small-molecule compounds capabl...
| Glavni autori: | , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Elsevier
2024-09-01
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| Serija: | iScience |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S2589004224019370 |