Seminal plasma metabolomics signatures of normosmic congenital hypogonadotropic hypogonadism

Background: Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare disease, whose pathogenesis remains unclear. Here, we conducted untargeted metabolomics and lipidomics to identify seminal plasma signatures of nCHH, and to study the effect of LH and FSH deficiency on semen. Methods: Tw...

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Bibliographic Details
Main Authors: Xiaogang Li, Ye Guo, Xi Wang, Haolong Li, Jiangfeng Mao, Songxin Yan, Guoju Luo, Renzhi Wang, Xueyan Wu, Yongzhe Li
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023019862