Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2
Introduction: Chirality is immanent in nature, and chiral molecules can achieve their pharmacological action through chiral matching with biomolecules and molecular conformation recognition. Objectives: Clinical translation of chiral therapeutics, particularly chiral peptide molecules, has been hamp...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
|
Series: | Journal of Advanced Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2090123222001217 |