Trends in Upstream and Downstream Process Development for Antibody Manufacturing

A steady increase of product titers and the corresponding change in impurity composition represent a challenge for development and optimization of antibody production processes. Additionally, increasing demands on product quality result in higher complexity of processes and analytics, thereby increa...

Full description

Bibliographic Details
Main Authors: Petra Gronemeyer, Reinhard Ditz, Jochen Strube
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Bioengineering
Subjects:
Online Access:http://www.mdpi.com/2306-5354/1/4/188