Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo

Spontaneous correlated activity is a universal hallmark of immature neural circuits. However, the cellular dynamics and intrinsic mechanisms underlying network burstiness in the intact developing brain are largely unknown. Here, we use two-photon Ca2+ imaging to comprehensively map the developmental...

Full description

Bibliographic Details
Main Authors: Jürgen Graf, Vahid Rahmati, Myrtill Majoros, Otto W Witte, Christian Geis, Stefan J Kiebel, Knut Holthoff, Knut Kirmse
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/82756