Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection

Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection

Abstract Ductal carcinoma in situ (DCIS) is a risk factor for the subsequent development of invasive breast cancer. High-risk features include age <45 years, size >5 cm, high-grade, palpable mass, hormone receptor negativity, and HER2 positivity. We have previously shown that immune infiltrate...

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Bibliographic Details
Main Authors: Alexa C. Glencer, Jasmine M. Wong, Nola M. Hylton, Gregor Krings, Emma McCune, Harriet T. Rothschild, Tristan A. Loveday, Michael D. Alvarado, Laura J. Esserman, Michael J. Campbell
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00267-z

Internet

https://doi.org/10.1038/s41523-021-00267-z

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