Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

Glioblastoma (GBM) harbors a highly immunosuppressive tumor microenvironment (TME) which influences glioma growth. Major efforts have been undertaken to describe the TME on a single-cell level. However, human data on regional differences within the TME remain scarce. Here, we performed high-depth si...

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Bibliographic Details
Main Authors: Philip Schmassmann, Julien Roux, Steffen Dettling, Sabrina Hogan, Tala Shekarian, Tomás A Martins, Marie-Françoise Ritz, Sylvia Herter, Marina Bacac, Gregor Hutter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-12-01
Series:eLife
Subjects:
glioblastoma
tumor microenvironment
scRNAseq
Online Access:https://elifesciences.org/articles/92678

Internet

https://elifesciences.org/articles/92678

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