Virus-like Particle Vaccines of Infectious Bursal Disease Virus Expressed in <i>Escherichia coli</i> Are Highly Immunogenic and Protect against Virulent Strain

Virus-like Particle Vaccines of Infectious Bursal Disease Virus Expressed in <i>Escherichia coli</i> Are Highly Immunogenic and Protect against Virulent Strain

Objectives: Infectious bursal disease virus (IBDV) is a highly contagious, acutely infectious agent that causes immunosuppression in chickens. We expressed IBDV VP2 proteins in <i>Escherichia coli</i> (<i>E. coli</i>) to develop an effective virus-like-particles (VLPs) vaccin...

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Bibliographic Details
Main Authors: Pengchao Ji, Tiantian Li, Yanan Wu, Qi Zhao, Lu Li, Xuejian Shi, Wenting Jiang, Jiabin Wang, Panpan Wang, Tingting Wang, Dawei Jiang
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
infectious bursal disease virus (IBDV)
vaccine
adjuvant
immune
virus-like particles (VLPs)
Online Access:https://www.mdpi.com/1999-4915/15/11/2178

Internet

https://www.mdpi.com/1999-4915/15/11/2178

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