GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.

GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.

Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands for a G protein-coupled receptor 54 (GPR54). Previous findings have shown that KISS1 acts as a metastasis suppressor in numerous cancers in humans. However, recent studies have demonstrated that an increase in...

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Bibliographic Details
Main Authors: Mateusz Zajac, Jeffrey Law, Dragana Donna Cvetkovic, Macarena Pampillo, Lindsay McColl, Cynthia Pape, Gianni M Di Guglielmo, Lynne M Postovit, Andy V Babwah, Moshmi Bhattacharya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3125256?pdf=render

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http://europepmc.org/articles/PMC3125256?pdf=render

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