The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death

The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death

The inflammasome is a conserved structure for the intracellular detection of danger or pathogen signals. As a large intracellular multiprotein signaling platform, it activates downstream effectors that initiate a rapid necrotic programmed cell death (PCD) termed pyroptosis and activation and secreti...

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Bibliographic Details
Main Authors: Eva Hasel de Carvalho, Shivani S Dharmadhikari, Kateryna Shkarina, Jingwei Rachel Xiong, Bruno Reversade, Petr Broz, Maria Leptin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
0ptogenetics
zebrafish
epithelial cells
inflammasome
cell death
ASC speck
Online Access:https://elifesciences.org/articles/86373

Internet

https://elifesciences.org/articles/86373

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