Symmetrical dimethylation of H4R3: A bridge linking DNA damage and repair upon oxidative stress
The DNA lesions caused by oxidative damage are principally repaired by the base excision repair (BER) pathway. 8-oxoguanine DNA glycosylase 1 (OGG1) initiates BER through recognizing and cleaving the oxidatively damaged nucleobase 8-oxo-7,8-dihydroguanine (8-oxoG). How the BER machinery detects and...
Main Authors: | Zhuang Ma, Wentao Wang, Shiwei Wang, Xingqi Zhao, Ying Ma, Congye Wu, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720308582 |
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