Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNA
Summary: Plasma cell-free DNA is being widely explored as a biomarker for clinical screening. Currently, methods are optimized for the extraction and detection of double-stranded mononucleosomal cell-free DNA of ∼160bp in length. We introduce uscfDNA-seq, a single-stranded cell-free DNA next-generat...
| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Elsevier
2022-07-01
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| 丛编: | iScience |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S2589004222008264 |