RNA Sequencing of Primary Cutaneous and Breast-Implant Associated Anaplastic Large Cell Lymphomas Reveals Infrequent Fusion Transcripts and Upregulation of PI3K/AKT Signaling via Neurotrophin Pathway Genes

RNA Sequencing of Primary Cutaneous and Breast-Implant Associated Anaplastic Large Cell Lymphomas Reveals Infrequent Fusion Transcripts and Upregulation of PI3K/AKT Signaling via Neurotrophin Pathway Genes

Cutaneous and breast implant-associated anaplastic large-cell lymphomas (cALCLs and BI-ALCLs) are two localized forms of peripheral T-cell lymphomas (PTCLs) that are recognized as distinct entities within the family of ALCL. JAK-STAT signaling is a common feature of all ALCL subtypes, whereas DUSP22...

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Bibliographic Details
Main Authors: Arianna Di Napoli, Davide Vacca, Giorgio Bertolazzi, Gianluca Lopez, Maria Piane, Aldo Germani, Evelina Rogges, Giuseppina Pepe, Fabio Santanelli Di Pompeo, Marzia Salgarello, Vaidehi Jobanputra, Susan Hsiao, Kazimierz O. Wrzeszczynski, Emilio Berti, Govind Bhagat
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
ALCL
fusion transcripts
transcriptome
PI3K/Akt pathway
NTRK signaling
Online Access:https://www.mdpi.com/2072-6694/13/24/6174

Internet

https://www.mdpi.com/2072-6694/13/24/6174

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