Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA

Epigenetically targeted therapeutic development, particularly for SAM-dependent methylations of DNA, mRNA and histones has been proceeding rapidly for cancer treatments over the past few years. However, this approach has barely begun to be exploited for developing new antibiotics, despite an overwhe...

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书目详细资料
Main Authors: Jujun Zhou, John R. Horton, Dan Yu, Ren Ren, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng
格式: 文件
语言:English
出版: Taylor & Francis Group 2022-09-01
丛编:Epigenetics
主题:
在线阅读:http://dx.doi.org/10.1080/15592294.2021.1976910