Overexpressing eukaryotic elongation factor 1 alpha (eEF1A) proteins to promote corticospinal axon repair after injury

Abstract Although protein synthesis is hypothesized to have a pivotal role in axonal repair after central nervous system (CNS) injury, the role of core components of the protein synthesis machinery has not been examined. Notably, some elongation factors possess non-canonical functions that may furth...

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Bibliographic Details
Main Authors: Daniel Romaus-Sanjurjo, Junmi M. Saikia, Hugo J. Kim, Kristen M. Tsai, Geneva Q. Le, Binhai Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01186-z