Oncological transformation in vitro of hepatic progenitor cell lines isolated from adult mice
Abstract Colorectal cancer cells can transfer the oncogene KRAS to distant cells, predisposing them to malignant transformation (Genometastasis Theory). This process could contribute to liver metastasis; besides, hepatic progenitor cells (HPCs) have been found to be involved in liver malignant neopl...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-06427-w |