Deep neural network based tissue deconvolution of circulating tumor cell RNA
Abstract Prior research has shown that the deconvolution of cell-free RNA can uncover the tissue origin. The conventional deconvolution approaches rely on constructing a reference tissue-specific gene panel, which cannot capture the inherent variation present in actual data. To address this, we have...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | Journal of Translational Medicine |
Online Access: | https://doi.org/10.1186/s12967-023-04663-w |