The UK BiLEVE and Mendelian randomisation: using multivariable instrumental variables to address “damned if you, damned if you don’t” adjustment problems

Abstract Objective To explore the use of multivariable instrumental variables to resolve the “damned if you do, damned if you don’t” adjustment problem created for Mendelian randomisation (MR) analysis using the smoking or lung function related phenotypes in the UK Biobank (UKB). Result “damned if y...

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Bibliographic Details
Main Authors: Benjamin Woolf, Dipender Gill, Hannah Sallis, Marcus R. Munafò
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Research Notes
Online Access:https://doi.org/10.1186/s13104-023-06434-8