Potential Therapeutic Effects of Long-Term Stem Cell Administration: Impact on the Gene Profile and Kidney Function of PKD/Mhm (Cy/+) Rats

Potential Therapeutic Effects of Long-Term Stem Cell Administration: Impact on the Gene Profile and Kidney Function of PKD/Mhm (Cy/+) Rats

Cystic kidney disease (CKD) is a heterogeneous group of genetic disorders and one of the most common causes of end-stage renal disease. Here, we investigate the potential effects of long-term human stem cell treatment on kidney function and the gene expression profile of PKD/Mhm (Cy/+) rats. Human a...

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Bibliographic Details
Main Authors: Daniela Nardozi, Stefania Palumbo, Arif ul Maula Khan, Carsten Sticht, Karen Bieback, Samar Sadeghi, Mark Andreas Kluth, Michael Keese, Norbert Gretz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
cystic kidney disease (CKD)
adipose-derived stromal cell (ASC)
ABCB5
conditioned media
gene expression profile
Online Access:https://www.mdpi.com/2077-0383/11/9/2601

Internet

https://www.mdpi.com/2077-0383/11/9/2601

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