Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer

Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer

Improving the chemotherapy sensitivity of bladder cancer is a current clinical challenge. It is critical to seek out effective combination therapies that include low doses of cisplatin due to its dose-limiting toxicity. This study aims to investigate the cytotoxic effects of the combination therapy...

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Bibliographic Details
Main Authors: Hatice Sevim Nalkiran, Dilara Akcora Yildiz, Faruk Saydam, Ali Irfan Guzel, Ihsan Nalkiran
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Saudi Journal of Biological Sciences
Subjects:
Bladder cancer
Small-molecule inhibitor
ProTAME, Cisplatin
Gemcitabine
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X23000098

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http://www.sciencedirect.com/science/article/pii/S1319562X23000098

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