Emerging role of RNA sensors in tumor microenvironment and immunotherapy

Abstract RNA sensors detect foreign and endogenous RNAs to protect the host by initiating innate and adaptive immune response. In tumor microenvironment (TME), activation of RNA sensors induces tumor-inhibitory cytotoxic T lymphocyte responses and inhibits the activity of immunosuppressive cells tho...

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Bibliographic Details
Main Authors: Rui Yang, Sihui Yu, Tianhan Xu, Jiawen Zhang, Sufang Wu
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-022-01261-z