The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

Abstract Entero virus 71 (EV71) causes hand, foot, and mouth disease (HFMD) and occasionally leads to severe neurological complications and even death. Scavenger receptor class B member 2 (SCARB2) is a functional receptor for EV71, that mediates viral attachment, internalization, and uncoating. Howe...

Full description

Bibliographic Details
Main Authors: Xuyuan Zhang, Pan Yang, Nan Wang, Jialong Zhang, Jingyun Li, Hao Guo, Xiangyun Yin, Zihe Rao, Xiangxi Wang, Liguo Zhang
Format: Article
Language:English
Published: Oxford University Press 2017-04-01
Series:Protein & Cell
Subjects:
SCARB2
EV71
monoclonal antibody
HFMD
receptor
Online Access:http://link.springer.com/article/10.1007/s13238-017-0405-7

Internet

http://link.springer.com/article/10.1007/s13238-017-0405-7

Similar Items