MicroRNA–disease Network Analysis Repurposes Methotrexate for the Treatment of Abdominal Aortic Aneurysm in Mice

MicroRNA–disease Network Analysis Repurposes Methotrexate for the Treatment of Abdominal Aortic Aneurysm in Mice

Abdominal aortic aneurysm (AAA) is a permanent dilatation of the abdominal aorta and is highly lethal. The main purpose of the current study is to search for noninvasive medical therapies for AAA, for which there is currently no effective drug therapy. Network medicine represents a cutting-edge tech...

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Bibliographic Details
Main Authors: Yicong Shen, Yuanxu Gao, Jiangcheng Shi, Zhou Huang, Rongbo Dai, Yi Fu, Yuan Zhou, Wei Kong, Qinghua Cui
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Abdominal aortic aneurysm
Network medicine
MicroRNA-derived disease network
Autoimmune disease
Methotrexate
Online Access:http://www.sciencedirect.com/science/article/pii/S167202292200095X

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http://www.sciencedirect.com/science/article/pii/S167202292200095X

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