Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2

Abstract SARS-CoV-2 can infect human cells through the recognition of the human angiotensin-converting enzyme 2 receptor. This affinity is given by six amino acid residues located in the variable loop of the receptor binding domain (RBD) within the Spike protein. Genetic recombination involving bat...

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Bibliographic Details
Main Authors: Luis Roger Esquivel Gomez, Ariane Weber, Arthur Kocher, Denise Kühnert
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50952-1