Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice

Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice

Background and aims: Hypercholesterolemia is a major risk factor for atherosclerosis and cardiovascular diseases. Although resistant to hypercholesterolemia, the mouse is a prominent model in cardiovascular research. To assess the contribution of bile acids to this protective phenotype, we explored...

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Bibliographic Details
Main Authors: Dany Gaillard, David Masson, Erwan Garo, Maamar Souidi, Jean-Paul Pais de Barros, Kristina Schoonjans, Jacques Grober, Philippe Besnard, Charles Thomas
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
bile acids
cholesterol
hypercholesterolemia
LXR
FXR
Online Access:https://www.mdpi.com/1422-0067/22/13/7163

Internet

https://www.mdpi.com/1422-0067/22/13/7163

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