The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

Abstract Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the cardiovascular system, the virus enters the cells by binding to the transmembrane form of ACE2 causing detrimental effects espec...

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Bibliographic Details
Main Authors: Sona Cacanyiova, Martina Cebova, Fedor Simko, Tomas Baka, Iveta Bernatova, Michal Kluknavsky, Stefan Zorad, Katarina Krskova, Ezgi Shaman, Anna Zemancikova, Andrej Barta, Basak G. Aydemir, Andrea Berenyiova
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Biological Research
Subjects:
Essential Hypertension
ACE2 inhibitor
Zofenopril, SARS-CoV-2
Cardiac function
Vasoactivity
Hydrogen sulfide
Online Access:https://doi.org/10.1186/s40659-023-00466-x

Internet

https://doi.org/10.1186/s40659-023-00466-x

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