Regulation of p53 by the mitotic surveillance/stopwatch pathway: implications in neurodevelopment and cancer
The transcription factor p53 (encoded by TP53) plays diverse roles in human development and disease. While best known for its role in tumor suppression, p53 signaling also influences mammalian development by triggering cell fate decisions in response to a wide variety of stresses. After over 4 decad...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-09-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2024.1451274/full |