A novel heavy domain antibody library with functionally optimized complementarity determining regions.

Today a number of synthetic antibody libraries of different formats have been created and used for the selection of a large number of recombinant antibodies. One of the determining factors for successful isolation of recombinant antibodies from libraries lies in the quality of the libraries i.e. the...

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Bibliographic Details
Main Authors: Ole Aalund Mandrup, Niels Anton Friis, Simon Lykkemark, Jesper Just, Peter Kristensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792991?pdf=render