Photo-induced copper-catalyzed sequential 1,n-HAT enabling the formation of cyclobutanols

Cyclobutanols are difficult structures to access given their inherent ring strain. Here, the authors present a method to form substituted cyclobutanols from a photocatalytic cascade reaction, proceeding via a 1,5- or 1,6-hydrogen atom transfer and subsequent ring closure.

Bibliographic Details
Main Authors: Zhusong Cao, Jianye Li, Guozhu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26670-5