In silico Analysis of Combinatorial microRNA Activity Reveals Target Genes and Pathways Associated with Breast Cancer Metastasis

Abstract Aberrant microRNA activity has been reported in many diseases, and studies often find numerous microRNAs concurrently dysregulated. Most target genes have binding sites for multiple microRNAs, and mounting evidence indicates that it is important to consider their combinatorial effect on tar...

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Bibliographic Details
Main Authors: Alan A. Dombkowski, Zakia Sultana, Douglas B. Craig, Hasan Jamil
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S6631