FluoroTensor: Identification and tracking of colocalised molecules and their stoichiometries in multi-colour single molecule imaging via deep learning

FluoroTensor: Identification and tracking of colocalised molecules and their stoichiometries in multi-colour single molecule imaging via deep learning

The identification of photobleaching steps in single molecule fluorescence imaging is a well-established procedure for analysing the stoichiometries of molecular complexes. Nonetheless, the method is challenging with protein fluorophores because of the high levels of noise, rapid bleaching and highl...

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Bibliographic Details
Main Authors: Max F.K. Wills, Carlos Bueno Alejo, Nikolas Hundt, Andrew J. Hudson, Ian C. Eperon
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Single molecule imaging
Colocalisation
Stoichiometries of protein fluorophores
Convolutional neural networks
Single particle tracking
Diffusion parameters
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702400028X

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http://www.sciencedirect.com/science/article/pii/S200103702400028X

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