Expediting Disulfiram Assays through a Systematic Analytical Quality by Design Approach

Expediting Disulfiram Assays through a Systematic Analytical Quality by Design Approach

An Analytical Quality by Design (AQbD) approach is presented, aiming at the development and validation of an HPLC method for the quantification of disulfiram and copper diethyldithiocarbamate in lipid nanoparticles. Following the definition of the analytical target profile (ATP), encompassing the cr...

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Bibliographic Details
Main Authors: João Basso, Maria Luísa Ramos, Alberto Pais, Rui Vitorino, Ana Fortuna, Carla Vitorino
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Chemosensors
Subjects:
AQbD
cancer
central composite design
copper diethyldithiocarbamate
disulfiram
lipid nanoparticles
Online Access:https://www.mdpi.com/2227-9040/9/7/172

Internet

https://www.mdpi.com/2227-9040/9/7/172

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